1-Methylguanidine hydrochloride ( —— )

产品货号. M19576 CAS No. 21770-81-0

COA

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HNMR

HPLC

MSDS

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产品名称

1-Methylguanidine hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

1-Methylguanidine hydrochloride 是一种内源性代谢产物。
产品描述

Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure however it also exhibits anti-inflammatory effects. Methylguanidine is synthesized from creatinine concomitant with the synthesis of hydrogen peroxide from endogenous substrates in peroxisomes. Recent evidence suggests that methylguanidine significantly inhibits iNOS activity and TNF- release. This means that methylguandine can attenuate the degree of inflammation and tissue damage associated with endotoxic shock.
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体内实验

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通路

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靶点

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受体

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研究领域

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适应症

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1.Silwood CJ Lynch E Claxson AW Grootveld MC: 1H and (13)C NMR spectroscopic analysis of human saliva. J Dent Res. 2002 Jun;81(6):422-7.

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